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Methylation du tRNA dans des cultures de gonades de Carcinus maenas : Inhibition par un extrait purifie des glandes androgenes
Author(s) -
Tekitek Ali,
Berreur-Bonnenfant Josette,
Rojas Margarita,
Ferezou Jean-Pierre,
Barbier Michel,
Lederer Edgar
Publication year - 1977
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(77)80473-0
Subject(s) - carcinus maenas , biology , methylation , methionine , microbiology and biotechnology , biochemistry , decapoda , zoology , crustacean , amino acid , dna
Subcultures of ovaries and testis of the crab Carcinus maenas have been performed in the presence of L‐[ Me ‐ 14 C]methionine. Introduction in the medium of a chromatographically‐purified liposoluble fraction from the androgenic glands of the same animal inhibits the biological methylation of the tRNA of the ovaries by 62%. The inhibition of methylation of five individual bases varies from 45% to 84%. No inhibition of tRNA methylation is observed under the same conditions with testis subcultures.