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Inhibition competitive de la Phé:tRNA ligase des embryons de ble par l'acide aurine tricarboxylique
Author(s) -
Carias J.R.,
Julien R.
Publication year - 1975
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(75)81114-8
Subject(s) - aminoacylation , dna ligase , chemistry , biochemistry , transfer rna , phenylalanine , microbiology and biotechnology , biology , amino acid , enzyme , rna , gene
Aurin tricarboxylic acid (A.T.A.), an inhibitor of protein biosynthesis (initiation and elongation steps), acts also as a competitive inhibitor of phenylalanine, in the ATP‐PP i exchange and tRNA Phe aminoacylation reactions catalysed by cytoplasmic wheat germ phenylalanine:tRNA ligase.