Premium
Etude in vitro de la synthese de la progesterone dans le corps jaune cyclique humain: Role de la prostaglandine F2α
Author(s) -
Santos Agostinho Almeida,
Hermier Claude,
Netter Albert
Publication year - 1973
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(73)80788-4
Subject(s) - chemistry , in vitro , receptor , stereochemistry , biochemistry
When HCG and PG F2α are added into the medium at their “maximal effective dose” the effect is supra‐maximal. In our experimental procedure, acetylsalicylic acid does not inhibit the synthesis of progesterone stimulated by LH. According to these results it seems that PG F2α is not the necessary membrane mediator between the hormonal‐receptor and the adenylcyclase system.