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L'acide N ‐glycolyl‐muramique, constituant des parois de Mycobacterium smegmatis : Identification par spectrometrie de masse
Author(s) -
Adam A.,
Petit J.F.,
Wietzerbin-Falszpan J.
Publication year - 1969
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(69)80203-6
Subject(s) - muramic acid , mycobacterium smegmatis , chemistry , disaccharide , stereochemistry , biochemistry , cell wall , peptidoglycan , mycobacterium tuberculosis , medicine , tuberculosis , pathology
The repeating disaccharide unit of the mucopeptide of the cell wall of Mycobacterium smegmatis contains N ‐acetyl‐glucosamine linked to N ‐glycolyl‐muramic acid. This first identification of N ‐glycolyl‐muramic acid as a natural product has been performed by mass spectrometry of the permethylated disaccharide. N ‐glycolyl muramic acid has been synthesized: the natural and synthetic products are identical.