Premium
Mise en evidence d'une reaction croisee entre les marqueurs allotypiques Aa1 et Aa2 du locus a chez le lapin
Author(s) -
Renneboog-Squilbin C.
Publication year - 1969
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(69)80028-1
Subject(s) - locus (genetics) , chemistry , microbiology and biotechnology , gene , stereochemistry , biology , biochemistry
It is well known that, in rabbits, the allotypes of the b locus carried by the light chains of the IgG molecules cross‐react. Nothing similar has been described for the allotypes of the a locus carried by the heavy chains of the IgG molecules. This paper describes a cross‐reaction between the rabbit allotypic markers Aa1 and Aa2 of the a locus. This phenomenon became evident in successive I 125 ‐labelled IgG precipitation experiments with a particular serum.