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Evidence for a three stranded complex between poly I and poly C
Author(s) -
Thiele Danielle,
Guschlbauer Wilhelm
Publication year - 1968
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(68)80052-3
Subject(s) - protonation , potentiometric titration , chemistry , titration , mixing (physics) , stoichiometry , phase diagram , crystallography , phase (matter) , stereochemistry , polymer chemistry , inorganic chemistry , physics , organic chemistry , ion , quantum mechanics
The conditions for the formation of a triple stranded semi‐protonated complex between polyinosinic (poly (I)) and polycytidylic acid (poly (C)) are described. From potentiometric titrations and mixing curves, the stoichiometry and a phase‐transition diagram is established between the partly protonated triple stranded and the unprotonated and completely protonated double helical complexes.