Premium
Evidence for more than one pathway in the formation of purine deoxyribonucleotides
Author(s) -
Foung A.,
Norman A.W.
Publication year - 1968
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(68)80012-2
Subject(s) - deoxyribonucleotides , purine , biochemistry , nucleotide , purine metabolism , context (archaeology) , chemistry , nucleic acid , biosynthesis , nucleoside , nucleotide salvage , biology , enzyme , gene , paleontology
The biosynthesis of purine deoxyribonucleotides was studied in the context of general purine nucleotide metabolism in the chick with the aid of radioactive nucleic acid precursors. Our results showed that in chick liver and intestine, the nucleoside phosphate reductase system so firmly established in E. coli [1] and L. leichmanni [2] is not exclusively responsible for the biosynthesis of purine deoxyribonucleotides.