Selective detection of HSO3− in living cells using a pyrroloquinoline structure containing turn-on fluorescent probe | Zendy

Jiahua Zhou | Zendy; Fa Wang | Zendy; Yuan-Xiang Xu | Zendy; Xuefang Gu | Zendy; Yujun Shi | Zendy; Bing Yang | Zendy

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Selective detection of HSO3− in living cells using a pyrroloquinoline structure containing turn-on fluorescent probe

Author(s) -

Jiahua Zhou,

Fa Wang,

Yuan-Xiang Xu,

Xuefang Gu,

Yujun Shi,

Bing Yang

Publication year - 2022

Publication title -

analytical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.392

H-Index - 73

eISSN - 1348-2246

pISSN - 0910-6340

DOI - 10.1007/s44211-022-00126-2

Subject(s) - chemistry , detection limit , fluorescence , turn (biochemistry) , molecular probe , linear range , stereochemistry , chromatography , biochemistry , optics , physics , dna

A turn-on fluorescence probe PQP-1 with a pyrroloquinoline skeleton has been designed and synthesized. Probe PQP-1 showed high sensitivity to HSO 3 - , low detection limit (16.83 nM), and a wide linear range (50-3000 μM). More importantly, probe PQP-1 could distinguish between HSO 3 - and SO 3 2- . Furthermore, cell imaging experiments of HSO 3 - in HeLa cells revealed that probe PQP-1 had potential application value in biological systems.

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