Open AccessSpectroscopic study of cyclen-based 19F NMR probe for detection of hydrogen sulfide
Author(s) -
Shigehiko Takegami,
Yuki Aramoto,
Atsuko Konishi
Publication year - 2022
Publication title -
analytical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 73
eISSN - 1348-2246
pISSN - 0910-6340
DOI - 10.1007/s44211-022-00100-y
Subject(s) - cyclen , chemistry , hydrogen sulfide , inorganic chemistry , stereochemistry , organic chemistry , sulfur
A cyclen-based 19 F NMR probe (F-cyclen) for hydrogen sulfide (H 2 S) has been prepared and evaluated for its complex formation ability with Cu 2+ ions and responsivity to H 2 S. F-Cyclen was readily synthesized by reacting cyclen with 4-(trifluoromethyl)benzyl bromide. Visible absorption spectrophotometry showed that, same as the original cyclen, F-cyclen formed a 1:1 complex with Cu 2+ ions. The 19 F NMR signal of F-cyclen at 16.5 ppm gradually decreased in intensity with increasing CuCl 2 concentration, with trifluoromethane sulfonic acid sodium salt (TFMSNa) used as an internal standard (0 ppm). When the Cu 2+ -F-cyclen complex was subjected to an increasing concentration of Na 2 S (as H 2 S donor), its corresponding 19 F NMR signal of F-cyclen at 16.5 ppm gradually increased in intensity. The regression curve between the 19 F NMR signal intensity ratio of F-cyclen to TFMSNa and Na 2 S concentration showed good linearity (r = 0.986) over the Na 2 S concentration range of 25-150 μM.