Open AccessHealing of Artificially Created Gap Non-union Using Autologous Cultured Osteoblasts Impregnated Over Three-Dimensional Biodegradable Scaffold: An Experimental Study (Rabbit)
Author(s) -
Vikas Kumar Singh,
Manish Kumar Singh,
Rupesh Jung Belbase,
Amit Rastogi
Publication year - 2021
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.1007/s43465-020-00288-z
Subject(s) - iliac crest , scaffold , medicine , bone healing , biomedical engineering , osteoblast , implant , in vivo , anatomy , surgery , in vitro , chemistry , biology , biochemistry , microbiology and biotechnology
The large bone defect often require bone transplant or its substitutes to restore bone integrity which have some limitations. The study was conducted to analyze role of autologous osteoblast that are amplified in vivo and impregnated in a synthesized three-dimensional gelatin hydroxyapatite scaffold for treating artificially created critical size defect in rabbit's iliac crest.