Open AccessAre Three Doses of Intravenous Tranexamic Acid more Effective than Single Dose in Reducing Blood Loss During Bilateral Total Knee Arthroplasty?
Author(s) -
Tarun Goyal,
Arghya Kundu Choudhury,
Tushar Gupta
Publication year - 2020
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.1007/s43465-020-00231-2
Subject(s) - medicine , tranexamic acid , anesthesia , tourniquet , perioperative , ecchymosis , surgery , regimen , total knee arthroplasty , blood transfusion , blood loss
Tranexamic acid (TXA) has shown to reduce perioperative blood loss after bilateral total knee arthroplasty (TKA). But dosage and schedule of administration are not clear in literature. This study was aimed to compare prospectively blood loss and transfusion requirement in bilateral TKA with 3-dose regimen versus a single intra-operative dose of intravenous TXA.