Open AccessCognition and cerebrovascular function in primary hyperparathyroidism before and after parathyroidectomy
Author(s) -
Miao LIU,
Melissa Sum,
Elaine Cong,
Ilma Colon,
Mariana Bucovsky,
John M. Williams,
Anna Kepley,
Jennifer H. Kuo,
J A Lee,
Ronald M. Lazar,
Randolph S. Marshall,
Shonni J. Silverberg,
Marcella D. Walker
Publication year - 2019
Publication title -
journal of endocrinological investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.034
H-Index - 84
eISSN - 1720-8386
pISSN - 0391-4097
DOI - 10.1007/s40618-019-01128-0
Subject(s) - parathyroidectomy , primary hyperparathyroidism , medicine , cerebral autoregulation , cognitive decline , neuropsychology , cognition , hyperparathyroidism , cardiology , psychology , autoregulation , parathyroid hormone , dementia , psychiatry , blood pressure , disease , calcium
There are cognitive changes in primary hyperparathyroidism (PHPT) that improve with parathyroidectomy, but the mechanism of cognitive dysfunction has not been delineated. We assessed if cerebrovascular function is impaired in PHPT, improves post-parathyroidectomy and is associated with PTH level and cognitive dysfunction.