Open AccessExtracellular Vesicles in Epstein-Barr Virus Pathogenesis
Author(s) -
Allaura S. Cone,
Sara B. York,
David G. Meckes
Publication year - 2019
Publication title -
current clinical microbiology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.657
H-Index - 16
ISSN - 2196-5471
DOI - 10.1007/s40588-019-00123-6
Subject(s) - pathogenesis , epstein–barr virus , microrna , biology , virus , viral pathogenesis , microvesicles , extracellular vesicles , extracellular , extracellular vesicle , immunology , virology , microbiology and biotechnology , viral replication , gene , genetics
Epstein-Barr virus (EBV) is a known determinant for numerous malignancies and may contribute to autoimmune diseases. The underlining mechanisms behind EBV pathologies is not completely understood. Recently, extracellular vesicles (EVs) released from infected cells have been found to produce profound effects on cellular microenvironments. Therefore, in this review we sought to critically evaluate the roles of EVs in EBV pathogenesis and assess their potential therapeutic and diagnostic utility.