Open AccessCell Types in Environmental Epigenetic Studies: Biological and Epidemiological Frameworks
Author(s) -
Kyle A Campbell,
Justin A. Colacino,
Sung Kyun Park,
Kelly M. Bakulski
Publication year - 2020
Publication title -
current environmental health reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 39
ISSN - 2196-5412
DOI - 10.1007/s40572-020-00287-0
Subject(s) - epigenetics , dna methylation , biology , computational biology , disease , cell type , bioinformatics , genetics , cell , medicine , pathology , gene expression , gene
This article introduces the roles of perinatal DNA methylation in human health and disease, highlights the challenges of tissue and cellular heterogeneity to studying DNA methylation, summarizes approaches to overcome these challenges, and offers recommendations in conducting research in environmental epigenetics.