Open AccessFlame Retardants and Neurodevelopment: an Updated Review of Epidemiological Literature
Author(s) -
Ann M. Vuong,
Kimberly Yolton,
Kim M. Cecil,
Joseph M. Braun,
Bruce P. Lanphear,
Aimin Chen
Publication year - 2020
Publication title -
current epidemiology reports
Language(s) - English
Resource type - Journals
ISSN - 2196-2995
DOI - 10.1007/s40471-020-00256-z
Subject(s) - polybrominated diphenyl ethers , tetrabromobisphenol a , neurotoxicity , polybrominated biphenyls , environmental chemistry , fire retardant , hexabromocyclododecane , chemistry , toxicity , organic chemistry , pollutant
Flame retardant (FR) compounds can adversely impact neurodevelopment. This updated literature review summarizes epidemiological studies of FRs and neurotoxicity published since 2015, covering historical (polybrominated biphenyls [PBBs], polychlorinated biphenyls [PCBs]), contemporary (polybrominated diphenyl ethers [PBDEs], hexabromocyclododecane [HBCD], and tetrabromobisphenol A [TBBPA]), and current-use organophosphate FRs (OPFRs) and brominated FRs (2-ethylhexyl 2,3,4,5-tetrabromobezoate [EH-TBB] TBB), bis(2-ethylhexyl) tetrabromophthalate [BEH-TEBP]), focusing on prenatal and postnatal periods of exposure.