Open AccessAssociations of Metals and Neurodevelopment: a Review of Recent Evidence on Susceptibility Factors
Author(s) -
Julia Anglen Bauer,
Victoria Fruh,
Caitlin G. Howe,
Roberta F. White,
Birgit Claus Henn
Publication year - 2020
Publication title -
current epidemiology reports
Language(s) - English
Resource type - Journals
ISSN - 2196-2995
DOI - 10.1007/s40471-020-00249-y
Subject(s) - effect modification , methylmercury , medicine , environmental health , physiology , biology , confidence interval , ecology , bioaccumulation
Epidemiologic evidence exists that many metals are associated with adverse neurobehavioral effects in young children, including lead (Pb), methylmercury (meHg), manganese (Mn) and arsenic (As) 5-8 . Importantly, chemical insult can vary depending on host factors and exposure circumstance. This systematic review summarizes the recent literature investigating modifying factors of the associations between metals and neurodevelopment, including immutable traits (sex or genetics) or exposure conditions (timing or co-exposures).