Open AccessSex-Specific Neurotoxic Effects of Early-Life Exposure to Fluoride: a Review of the Epidemiologic and Animal Literature
Author(s) -
Rivka Green,
Joshua Rubenstein,
Reynaldo Popoli,
Ronamae Capulong,
Christine Till
Publication year - 2020
Publication title -
current epidemiology reports
Language(s) - English
Resource type - Journals
ISSN - 2196-2995
DOI - 10.1007/s40471-020-00246-1
Subject(s) - animal studies , offspring , human studies , prenatal exposure , physiology , medicine , fluoride , animal model , cohort study , adverse effect , prenatal development , epidemiology , pregnancy , environmental health , biology , fetus , genetics , inorganic chemistry , chemistry
A growing body of evidence suggests adverse neurodevelopmental effects of early-life exposure to fluoride that may differ depending on timing of exposure and sex of the exposed. We conducted a literature search to identify the animal and human epidemiologic studies that examined sex-specific neurodevelopmental differences in response to prenatal and postnatal exposure to fluoride.