Risks of Cardiac Valve Regurgitation and Heart Failure Associated with Ergot- and Non-Ergot-Derived Dopamine Agonist Use in Patients with Parkinson’s Disease: A Systematic Review of Observational Studies
Author(s) -
Tanja Tran,
James M. Brophy,
Samy Suissa,
Christel Renoux
Publication year - 2015
Publication title -
cns drugs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.565
H-Index - 108
eISSN - 1179-1934
pISSN - 1172-7047
DOI - 10.1007/s40263-015-0293-4
Subject(s) - medicine , cabergoline , valvular heart disease , hazard ratio , cohort study , pergolide , cohort , heart failure , observational study , dopamine agonist , confidence interval , dopamine , prolactin , dopaminergic , hormone
Dopamine agonists (DAs) are commonly used in the therapy of Parkinson's disease (PD). However, several observational studies have suggested a putative association between DAs and specific cardiac adverse events.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom