Open AccessInfluence of alumina substrates open porosity on calcium phosphates formation produced by the biomimetic method
Author(s) -
Isabela R. Lavagnini,
João V. Campos,
Denise Osiro,
Julieta Adriana Ferreira,
Luiz Alberto Colnago,
Elíria Maria de Jesus Agnolon Pallone
Publication year - 2022
Publication title -
progress in biomaterials
Language(s) - English
Resource type - Journals
eISSN - 2194-0509
pISSN - 2194-0517
DOI - 10.1007/s40204-022-00193-8
Subject(s) - porosity , simulated body fluid , scanning electron microscope , calcium , materials science , biomaterial , chemical engineering , phase (matter) , phosphate , polyethylene , incubation , composite material , chemistry , metallurgy , nanotechnology , organic chemistry , biochemistry , engineering
We evaluated the influence of the open porosity of alumina (Al 2 O 3 ) substrates on the phase formation of calcium phosphates deposited onto it surface. The Al 2 O 3 substrates were prepared with different porosities by the foam-gelcasting method associated with different amounts of polyethylene beads. The substrates were coated biomimetically for 14 and 21 days of incubation in a simulated body fluid (SBF). Scanning electron microscopy characterisation and X-ray computed microtomography showed that the increase in the number of beads provided an increase in the open porosity. The X-ray diffraction and infrared spectroscopy showed that the biomimetic method was able to form different phases of calcium phosphates. It was observed that the increase in the porosity favoured the formation of β-tricalcium phosphate for both incubation periods. The incubation period and the porosity of the substrates can influence the phases and the amount of calcium phosphates formed. Thus, it is possible to target the best application for the biomaterial produced.