Open AccessStructure based design, stability study and synthesis of the dinitrophenylhydrazone derivative of the oxidation product of lanosterol as a potential P. falciparum transketolase inhibitor and in-vivo antimalarial study
Author(s) -
Olatomide A. Fadare,
N.O. Omisore,
Oluwaseun B. Adegbite,
Oladoja Awofisayo,
Frank Abimbola Ogundolie,
Julius K. Adesanwo,
Craig A. Obafemi
Publication year - 2021
Publication title -
in silico pharmacology
Language(s) - English
Resource type - Journals
ISSN - 2193-9616
DOI - 10.1007/s40203-021-00097-8
Subject(s) - transketolase , lanosterol , chemistry , stereochemistry , docking (animal) , combinatorial chemistry , plasmodium falciparum , thiamine pyrophosphate , biochemistry , cofactor , enzyme , biology , malaria , sterol , cholesterol , immunology , medicine , nursing
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