Open AccessHemoglobin adducts as an important marker of chronic exposure to low concentration of 1, 3-butadiene
Author(s) -
Reza Ahmadkhaniha,
Faezeh Izadpanah,
Noushin Rastkari
Publication year - 2021
Publication title -
journal of environmental health science and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.447
H-Index - 45
ISSN - 2052-336X
DOI - 10.1007/s40201-021-00716-8
Subject(s) - hemoglobin , toxicology , cigarette smoke , 1,3 butadiene , occupational exposure , diesel exhaust , carcinogen , analysis of variance , medicine , physiology , diesel fuel , chemistry , environmental health , biology , biochemistry , organic chemistry , catalysis
1, 3-Butadiene is a famous industrial compound which occurs in gasoline and diesel exhaust and in cigarette smoke. Based on little evidence of carcinogenicity in laboratory animals and humans, it was classified as a probable carcinogen. The potential of exposure to gasoline and diesel exhaust containing these chemical compounds is very considerable in urban areas. According to studies, in estimation of workers' chronic exposure with biological samples, analysis of the concentration of related hemoglobin adducts seems to give the most valid estimation of exposure.