Open AccessGenomic medicine on the frontier of precision medicine
Author(s) -
Mandana Hasanzad,
Negar Sarhangi,
Anoosh Naghavi,
Ehsan Ghavimehr,
Fatemeh Khatami,
Sima Ehsani Chimeh,
Bagher Larijani,
Hamid Reza Aghaei Meybodi
Publication year - 2021
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-021-00880-6
Subject(s) - precision medicine , personalized medicine , context (archaeology) , pharmacogenomics , genomic medicine , genomics , data science , omics , computational biology , medicine , computer science , genome , bioinformatics , biology , genetics , pathology , paleontology , gene
Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine. The rapid growth of high-development technologies permits the assessment of biological systems. Study of the integrated profiles of omics, such as genome, transcriptome, proteome and other omics information lead to significant advances in personalized and precision medicine. In the context of precision medicine, pharmacogenomics can play an important role in order to discriminate responders and non-responders to medications and avoiding toxicity and achieving the optimum dose. So precision medicine in accordance with genomic medicine will transform medicine from conventional evidence-based medicine in the diagnosis and treatment towards precision based-medicine. In this review, we have summarized the related issues for genomic medicine and precision medicine.