The role of the PPARG (Pro12Ala) common genetic variant on type 2 diabetes mellitus risk | Zendy

Leila Hashemian | Zendy; Negar Sarhangi | Zendy; Mahdi Afshari | Zendy; Hamid Reza Aghaei Meybodi | Zendy; Mandana Hasanzad | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The role of the PPARG (Pro12Ala) common genetic variant on type 2 diabetes mellitus risk

Author(s) -

Leila Hashemian,

Negar Sarhangi,

Mahdi Afshari,

Hamid Reza Aghaei Meybodi,

Mandana Hasanzad

Publication year - 2021

Publication title -

journal of diabetes and metabolic disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.619

H-Index - 33

ISSN - 2251-6581

DOI - 10.1007/s40200-021-00872-6

Subject(s) - peroxisome proliferator activated receptor gamma , medicine , genotyping , type 2 diabetes , type 2 diabetes mellitus , insulin resistance , allele , endocrinology , sanger sequencing , allele frequency , population , diabetes mellitus , genotype , genetics , biology , peroxisome proliferator activated receptor , gene , mutation , receptor , environmental health

Type 2 diabetes (T2DM) prevalence has been rapidly increasing in the last decades. T2DM pathogenesis is related to insulin resistance and beta-cell dysfunction. Peroxisome proliferator-activated receptor gamma (PPARG) is concerned about T2DM risk through the involvement in adipocyte differentiation and energy homeostasis. The present study aimed to find the risk associated with a common genetic variant (Pro12Ala) of the PPARG gene in the development of T2DM in a group of the Iranian population.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research