Open AccessOcimum gratissimum enhances insulin sensitivity in male Wistar rats with dexamethasone-induced insulin resistance
Author(s) -
Shehu-Tijani Shittu,
Taye Jemilat Lasisi,
Seyid Alli-Sisse Shittu,
A. A. Adeyemi,
Tolulope Adeoye,
A R A Alada
Publication year - 2021
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-021-00850-y
Subject(s) - medicine , endocrinology , insulin resistance , hyperinsulinemia , insulin , dexamethasone , insulin tolerance test , steatosis , chemistry , insulin sensitivity
The antidiabetic activities of Ocimum gratissimum (OG) leaf extract are well documented in experimental diabetes induced by beta cell destruction resulting in hypoinsulinemia. There is however paucity of data on its effect in conditions characterized by hyperinsulinemia. This study therefore investigated the effect of OG on insulin resistance induced by dexamethasone in male Wistar rats.