Association of ACE I/D and PAI-1 4G/5G polymorphisms with susceptibility to type 2 diabetes mellitus | Zendy

Somaye Miri | Zendy; Mohammad Hasan Sheikhha | Zendy; Seyed Alireza Dastgheib | Zendy; Seyed Amir Shaker | Zendy; Hossein Neámatzadeh | Zendy

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Association of ACE I/D and PAI-1 4G/5G polymorphisms with susceptibility to type 2 diabetes mellitus

Author(s) -

Somaye Miri,

Mohammad Hasan Sheikhha,

Seyed Alireza Dastgheib,

Seyed Amir Shaker,

Hossein Neámatzadeh

Publication year - 2021

Publication title -

journal of diabetes and metabolic disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.619

H-Index - 33

ISSN - 2251-6581

DOI - 10.1007/s40200-021-00839-7

Subject(s) - odds ratio , medicine , genotype , type 2 diabetes mellitus , angiotensin converting enzyme , confidence interval , diabetes mellitus , plasminogen activator inhibitor 1 , gastroenterology , allele , case control study , plasminogen activator , allele frequency , endocrinology , genetics , biology , blood pressure , gene

A number of studies were carried out to assess the association of angiotensin I converting enzyme (ACE) I/D and plasminogen activator inhibitor-1 (PAI-1-1) 4G/5G polymorphisms with susceptibility to type 2 diabetes mellitus (T2DM). However, there are a few studies in Iranian patients with T2DM. Here, we tested for an association of ACE I/D and PAI-1 4G/5G polymorphisms with T2DM risk.

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