Open AccessAssociation of ACE I/D and PAI-1 4G/5G polymorphisms with susceptibility to type 2 diabetes mellitus
Author(s) -
Somaye Miri,
Mohammad Hasan Sheikhha,
Seyed Alireza Dastgheib,
Seyed Amir Shaker,
Hossein Neámatzadeh
Publication year - 2021
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-021-00839-7
Subject(s) - odds ratio , medicine , genotype , type 2 diabetes mellitus , angiotensin converting enzyme , confidence interval , diabetes mellitus , plasminogen activator inhibitor 1 , gastroenterology , allele , case control study , plasminogen activator , allele frequency , endocrinology , genetics , biology , blood pressure , gene
A number of studies were carried out to assess the association of angiotensin I converting enzyme (ACE) I/D and plasminogen activator inhibitor-1 (PAI-1-1) 4G/5G polymorphisms with susceptibility to type 2 diabetes mellitus (T2DM). However, there are a few studies in Iranian patients with T2DM. Here, we tested for an association of ACE I/D and PAI-1 4G/5G polymorphisms with T2DM risk.