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The effects of dietary/herbal supplements and the serum levels of micronutrients on the healing of diabetic foot ulcers in animal and human models: a systematic review
Author(s) -
Mohammad Reza Amini,
Maryam Aalaa,
Ensieh NasliEsfahani,
Rasha Atlasi,
Mahnaz Sanjari,
Nazli Namazi
Publication year - 2021
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-021-00793-4
Subject(s) - medicine , micronutrient , observational study , cochrane library , diabetic foot ulcer , diabetes mellitus , clinical trial , randomized controlled trial , medline , systematic review , animal studies , diabetic foot , vitamin e , nutritional supplementation , traditional medicine , pathology , endocrinology , antioxidant , biochemistry , chemistry , political science , law
Diabetic Foot Ulcer (DFU) is one of the common and serious complications in patients with Diabetes Mellitus (DM) worldwide. Given the considerable tendency of patients suffering from DFU to use the complementary therapies, the objectives of this study were to: (i) summarize the effects of dietary and herbal supplements on DFU characteristics and metabolic parameters in both animal models and clinical trials, and (ii) evaluate any links between the serum levels of micronutrients and DFU in observational studies.

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