Open AccessThe rate of aerobic glycolysis is a pivotal regulator of tumor progression
Author(s) -
Mohammad Erfan Zare,
Atefeh Nasir Kansestani,
Shahrooz Hemmati,
Kamran Mansouri,
Asad VaisiRaygani
Publication year - 2021
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-021-00774-7
Subject(s) - warburg effect , anaerobic glycolysis , glycolysis , extracellular , cell culture , intracellular , oxidative phosphorylation , carbohydrate metabolism , biology , chemistry , medicine , endocrinology , metabolism , biochemistry , genetics
Cancer cells depend on glucose metabolism via exclusive glycolysis pathway is named Aerobic glycolysis or Warburg effect. The aim of this study was investigation of different glucose accessibility conditions on the rate of Warburg effect and its impact on Hypoxia inducible factors-1 α (HIF-1 α)/vascular endothelium growth factor (VEGF) pathway in breast cancer cells lines.