Open AccessThe modulation of mature dendritic cells from patients with type 1 diabetes using human periodontal ligament stem cells. An in-vitro study
Author(s) -
L Ashour,
Rola Al Habashneh,
M M Al-Mrahelh,
Duaa Abuarqoub,
Yousef Khader,
Hanan Jafar,
Abdalla Awidi
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00602-4
Subject(s) - periodontal ligament stem cells , stem cell , dendritic cell , cd14 , immunology , follicular dendritic cells , microbiology and biotechnology , proinflammatory cytokine , biology , stromal cell , mesenchymal stem cell , flow cytometry , antigen presenting cell , inflammation , t cell , immune system , cancer research , biochemistry , alkaline phosphatase , enzyme
This in vitro study aimed to investigate whether human periodontal ligament stem cells isolated from impacted third molars can modify the maturation and phenotype of monocyte-derived dendritic cells pulsed with GAD-65 obtained from patients with type 1 diabetes.