Open AccessGut microbiota: a perspective of precision medicine in endocrine disorders
Author(s) -
Salman Shirvani Rad,
Amirabbas Nikkhah,
Mohammadmahdi Orvatinia,
HaniehSadat Ejtahed,
Negar Sarhangi,
Seyed Hamid Jamaldini,
Nazli Khodayari,
Hamid Reza Aghaei Meybodi,
Mandana Hasanzad
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00593-2
Subject(s) - gut flora , endocrine system , polycystic ovary , microbiome , gastrointestinal tract , biology , obesity , gut microbiome , thyroid , type 2 diabetes mellitus , dysbiosis , gut–brain axis , bioinformatics , physiology , medicine , hormone , diabetes mellitus , immunology , endocrinology , insulin resistance
Gut microbiota composition is unique in every individual, it impacts on organ functions that produce hormones. Gut microbiota composition balance is directly related to our general health status. This continual interaction between gut microbiota and endocrine organs sometimes can be considered as the etiology of diseases such as type 2 diabetes mellitus (T2DM), obesity, osteoporosis, polycystic ovary syndrome (PCOS), and thyroid diseases. Microbiota is introduced for a total collection of microbial organisms in our bodies and microbiome referred for their genome and their collective functions. Near 100 trillion microorganisms live in our body and almost all of them occupy the human gut gastrointestinal tract. Precision medicine can play a crucial role in health maintenance by affecting gut microbiota composition in every individual. It can also develop special treatments specifically for every individual. In this review, we addressed any correlation between gut microbiota and endocrine disorders including T2DM, obesity, PCOS, thyroid disorders and osteoporosis.