Open AccessMethylglyoxal and soluble RAGE in type 2 diabetes mellitus: Association with oxidative stress
Author(s) -
Alisha Reyaz,
Md. Sayem Alam,
Kailash Chandra,
Sunil Kohli,
Sarita Agarwal
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00543-y
Subject(s) - methylglyoxal , glycation , medicine , oxidative stress , diabetes mellitus , endocrinology , advanced glycation end product , type 2 diabetes mellitus , type 2 diabetes , rage (emotion) , hemoglobin , biochemistry , chemistry , biology , enzyme , neuroscience
Methylglyoxal (MGO) and MGO related advance end product (AGE) are thought to contribute to the development of diabetes and its complications. The present study was intended to determine plasma MGO and sRAGE levels in T2DM patients and to assess the relationship between MGO and other parameters, such as sRAGE and oxidative markers.