Gene set enrichment analysis of α-amylase and α-glucosidase inhibitors of Cassia glauca | Zendy

Shama G. Ternikar | Zendy; M. B. Patil | Zendy; Ismail Pasha | Zendy; Pukar Khanal | Zendy

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Gene set enrichment analysis of α-amylase and α-glucosidase inhibitors of Cassia glauca

Author(s) -

Shama G. Ternikar,

M. B. Patil,

Ismail Pasha,

Pukar Khanal

Publication year - 2020

Publication title -

journal of diabetes and metabolic disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.619

H-Index - 33

ISSN - 2251-6581

DOI - 10.1007/s40200-020-00538-9

Subject(s) - amylase , docking (animal) , chemistry , in silico , enzyme , cassia , ic50 , glycoside , in vitro , biochemistry , stereochemistry , gene , medicine , alternative medicine , nursing , traditional chinese medicine , pathology

The present study aimed to evaluate in vitro α-amylase and α-glucosidase inhibitory activity of various extracts of Cassia glauca, predict the binding affinity of multiple phytoconstituents with both enzymes via in silico molecular docking and identify the probably modulated pathways by the lead hit.

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