Open AccessGene set enrichment analysis of α-amylase and α-glucosidase inhibitors of Cassia glauca
Author(s) -
Shama G. Ternikar,
Manjusha Patil,
Ismail Pasha,
Pukar Khanal
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00538-9
Subject(s) - amylase , docking (animal) , chemistry , in silico , enzyme , cassia , ic50 , glycoside , in vitro , biochemistry , stereochemistry , gene , medicine , alternative medicine , nursing , traditional chinese medicine , pathology
The present study aimed to evaluate in vitro α-amylase and α-glucosidase inhibitory activity of various extracts of Cassia glauca, predict the binding affinity of multiple phytoconstituents with both enzymes via in silico molecular docking and identify the probably modulated pathways by the lead hit.