Open AccessHyssopus officinalis exerts hypoglycemic effects on streptozotocin-induced diabetic rats via modulating GSK-3β, C-fos, NF-κB, ABCA1 and ABGA1 gene expression
Author(s) -
Rehab M. AbdelMegeed,
Samah A. El Newary,
Mai O. Kadry,
Hassan Z. Ghanem,
Rabeh ElShesheny,
Hussein A. H. Said-Al Ahl,
Abdel-Hamid Z. Abdel-Hamid
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00535-y
Subject(s) - streptozotocin , pharmacology , abcg1 , medicine , officinalis , diabetes mellitus , abca1 , traditional medicine , biochemistry , endocrinology , biology , gene , transporter
Type 2 diabetes mellitus (DMT2) is contributed to dual interactions between environmental factors and certain genetic factors. This impressed a great need for novel treatment strategy. Nevertheless, Hyssopus officinalis ( H. officinalis) as a terrestrial herb is considered to be an important source of natural antioxidants, it could be assessed as an anti-hyperglycemic agent.