Open AccessImproving effect of combined inorganic nitrate and nitric oxide synthase inhibitor on pancreatic oxidative stress and impaired insulin secretion in streptozotocin induced-diabetic rats
Author(s) -
Zahra Shabgard Shahraki,
Narges Karbalaei,
Marzieh Nemati
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00516-1
Subject(s) - medicine , endocrinology , insulin , streptozotocin , diabetes mellitus , chemistry , oxidative stress , pancreas , pancreatic islets , nitric oxide synthase , sodium nitrate , islet , nitric oxide , organic chemistry
The aim of this study was to evaluate the effect of dietary nitrate on secretory function of pancreatic islet and oxidative stress status in streptozotocin (STZ) induced type 1 diabetes in absence or presence of nitric oxide synthase inhibitor (L-NAME).