Open AccessThe influence of P-glycoprotein expression in the standard treatment of Helicobacter pylori infection in Sprague Dawley rats
Author(s) -
Noor Safwah Damanhuri,
Endang Kumolosasi,
Marhanis Salihah Omar,
Amirul Faiz Abd Razak,
Ahmad Hasnan Mansor
Publication year - 2021
Publication title -
daru
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 42
eISSN - 2008-2231
pISSN - 1560-8115
DOI - 10.1007/s40199-020-00377-2
Subject(s) - omeprazole , p glycoprotein , helicobacter pylori , inducer , western blot , medicine , pharmacology , stomach , efflux , antibiotics , chemistry , biology , microbiology and biotechnology , multiple drug resistance , biochemistry , gene
P-glycoprotein (P-gp) is an Adenosine triphosphate (ATP) dependent drug-efflux pump which is located abundantly in the stomach and protects the gut mucosa from xenobiotic.