Open AccessCardenolide-rich fraction of Pergularia tomentosa as a novel Antiangiogenic agent mainly targeting endothelial cell migration
Author(s) -
Mahya Hosseini,
Mahdi Ayyari,
Anna Meyfour,
Sonia Piacente,
Antonietta Cerulli,
Alexander D. Crawford,
Sara Pahlavan
Publication year - 2020
Publication title -
daru
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 42
eISSN - 2008-2231
pISSN - 1560-8115
DOI - 10.1007/s40199-020-00356-7
Subject(s) - chorioallantoic membrane , umbilical vein , biology , angiogenesis , human umbilical vein endothelial cell , in vivo , endothelial stem cell , microbiology and biotechnology , pharmacology , in vitro , biochemistry , cancer research
Angiogenesis related abnormalities underlie several life-threatening disorders. Despite approved therapies, scientists have yet to develop highly efficient, low cost approaches with minimal side effects.