Open AccessAn Update on the Role of Common Genetic Variation Underlying Substance Use Disorders
Author(s) -
Emma C. Johnson,
Yoonhoo Chang,
Arpana Agrawal
Publication year - 2020
Publication title -
current genetic medicine reports
Language(s) - English
Resource type - Journals
ISSN - 2167-4876
DOI - 10.1007/s40142-020-00184-w
Subject(s) - cannabis , addiction , pleiotropy , adh1b , psychiatric genetics , substance use , genome wide association study , biology , psychology , psychiatry , genetics , medicine , single nucleotide polymorphism , gene , schizophrenia (object oriented programming) , branched chain alpha keto acid dehydrogenase complex , biochemistry , enzyme , genotype , dehydrogenase , phenotype
Sample size increases have resulted in novel and replicable loci for substance use disorders (SUDs). We summarize some of the latest insights into SUD genetics and discuss some next steps in addiction genetics.