Open AccessDiabetic Vasculopathy: Macro and Microvascular Injury
Author(s) -
Roberto Mota,
Samuel E Morgan,
Edward Moreira Bahnson
Publication year - 2020
Publication title -
current pathobiology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.177
H-Index - 24
ISSN - 2167-485X
DOI - 10.1007/s40139-020-00205-x
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , macrovascular disease , insulin resistance , disease , vascular disease , intensive care medicine , diabetic angiopathy , cardiology , endocrinology
Diabetes is a common and prevalent medical condition as it affects many lives around the globe. Specifically, type-2 Diabetes (T2D) is characterized by chronic systemic inflammation alongside hyperglycemia and insulin resistance in the body, which can result in atherosclerotic legion formation in the arteries and thus progression of related conditions called diabetic vasculopathies. T2D patients are especially at risk for vascular injury; adjunct in many of these patients heir cholesterol and triglyceride levels reach dangerously high levels and accumulate in the lumen of their vascular system.