Open AccessNext-Generation Techniques for Determination of Protein-Protein Interactions: Beyond the Crystal Structure
Author(s) -
Rachel Carter,
Alessandra Luchini,
Lance A. Liotta,
Amanda Haymond
Publication year - 2019
Publication title -
current pathobiology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.177
H-Index - 24
ISSN - 2167-485X
DOI - 10.1007/s40139-019-00198-2
Subject(s) - drug discovery , druggability , protein crystallization , structural biology , identification (biology) , nanotechnology , structural bioinformatics , computational biology , mass spectrometry , resolution (logic) , computer science , chemistry , protein structure , materials science , biology , artificial intelligence , biochemistry , organic chemistry , crystallization , botany , chromatography , gene
We discuss recent advancements in structural biology methods for investigating sites of protein-protein interactions. We will inform readers outside the field of structural biology about techniques beyond crystallography, and how these different technologies can be utilized for drug development.