
An Evaluation of Staphylococci from Ocular Surface Infections Treated Empirically with Topical Besifloxacin: Antibiotic Resistance, Molecular Characteristics, and Clinical Outcomes
Author(s) -
Barry A. Schechter,
John D. Sheppard,
Christine M Sanfilippo,
Heleen H DeCory,
Penny A. Asbell
Publication year - 2019
Publication title -
ophthalmology and therapy
Language(s) - English
Resource type - Journals
eISSN - 2193-6528
pISSN - 2193-8245
DOI - 10.1007/s40123-019-00223-y
Subject(s) - staphylococcus epidermidis , antibiotics , microbiology and biotechnology , ciprofloxacin , medicine , staphylococcus aureus , sccmec , antibiotic resistance , bacterial conjunctivitis , staphylococcal infections , methicillin resistant staphylococcus aureus , biology , bacteria , genetics
Understanding antibiotic resistance and toxin profiles among staphylococcal isolates in ocular infections can aid in therapeutic management and infection prevention strategies. We evaluated in vitro antibiotic resistance patterns and molecular traits of staphylococci isolated from patients with ocular surface infections. We also report on clinical outcomes for these patients following empirical treatment with topical besifloxacin ophthalmic suspension 0.6%.