Open AccessEnhancing the Angiogenic and Proliferative Capacity of Dermal Fibroblasts with Mulberry (Morus alba. L) Root Extract
Author(s) -
Jisoo Im,
Jiyu Hyun,
Sung-Won Kim,
Suk Ho Bhang
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-021-00404-6
Subject(s) - paracrine signalling , angiogenesis , dermis , umbilical vein , hair follicle , microbiology and biotechnology , cell growth , epidermis (zoology) , secretion , biology , chemistry , andrology , cancer research , endocrinology , medicine , biochemistry , anatomy , in vitro , receptor
Enhancing blood flow and cell proliferation in the hair dermis is critical for treating hair loss. This study was designed to aid the development of alternative and effective solutions to overcome alopecia. Specifically, we examined the effects of Morus alba. L root extract (MARE, which has been used in traditional medicine as a stimulant for hair proliferation) on dermal fibroblasts and other cell types found in the epidermis.