Open AccessPreparation and In Vitro Characterization of Gelatin Methacrylate for Corneal Tissue Engineering
Author(s) -
Yayun Yan,
Yanyan Cao,
Rong Cheng,
Zhizhong Shen,
Yajing Zhao,
Yixia Zhang,
Guohong Zhou,
Shengbo Sang
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-021-00393-6
Subject(s) - biocompatibility , mesenchymal stem cell , tissue engineering , gelatin , scaffold , stromal cell , biomedical engineering , self healing hydrogels , cornea , chemistry , stem cell , microbiology and biotechnology , materials science , pathology , ophthalmology , biology , medicine , biochemistry , polymer chemistry , organic chemistry
Corneal disease is second only to cataract considered as the leading cause of blindness in the world, with high morbidity. Construction of corneal substitutes in vitro by tissue engineering technology to achieve corneal regeneration has become a research hotspot in recent years. We conducted in-depth research on the biocompatibility, physicochemical and mechanical properties of rat bone marrow mesenchymal stem cells (rBM-MSCs)-seeded gelatin methacrylate (GelMA) as a bioengineered cornea.