Open AccessA Freezing and Thawing Method for Fabrication of Small Gelatin Nanoparticles with Stable Size Distributions for Biomedical Applications
Author(s) -
Yonghyun Gwon,
Woochan Kim,
Sunho Park,
Suk-Jin Hong,
Jangho Kim
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-021-00380-x
Subject(s) - gelatin , biocompatibility , nanoparticle , materials science , drug delivery , nanotechnology , polymer , tissue engineering , fabrication , biomedical engineering , chemistry , composite material , organic chemistry , pathology , metallurgy , medicine , alternative medicine
Gelatin, a natural polymer, has a number of advantages as a material for fabricating nanoparticles, such as its hydrophilicity, biodegradability, nontoxicity, and biocompatibility, as well as low cost. Despite these various advantages, gelatin-based nanoparticles still have critical limitation for biomedical applications due to their relatively larger size than those of other materials.