Open AccessA Novel Hypothesis and Characterization to Isolate Microvascular Endothelial Cells Simultaneously with Adipose-Derived Stem Cells from the Human Adipose-Derived Stromal Vascular Fraction
Author(s) -
Yeon Hee Ryu,
SukHo Moon,
Ki Joo Kim,
Young Joon Jun,
Deuk Young Oh,
SangHeon Kim,
JongWon Rhie
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-021-00332-5
Subject(s) - stromal vascular fraction , adipose tissue , stromal cell , vasculogenesis , biology , microbiology and biotechnology , endothelial stem cell , angiogenesis , stem cell , population , tissue engineering , in vitro , progenitor cell , medicine , endocrinology , cancer research , biochemistry , genetics , environmental health
Angiogenesis and vasculogenesis are essential processes for successful tissue regeneration in tissue engineering and regenerative medicine. The adipose-derived stromal vascular fraction (SVF) is not only a source of adipose stem cells (ASC) but also a suitable source of microvascular endothelial cells because it is a rich capillary network. So, we propose a new hypothesis for isolating adipose-derived human microvascular endothelial cells (HMVEC-A) from the SVF and developed a dual isolation system that isolates two cell types from one tissue.