Open AccessPeripheral Nerve Regeneration Using a Nerve Conduit with Olfactory Ensheathing Cells in a Rat Model
Author(s) -
Jong-Yoon Lee,
YoungHo Kim,
BooYoung Kim,
Dae-Hyun Jang,
SungWook Choi,
So-Hyun Joen,
Hyungyun Kim,
Sang-Uk Lee
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00326-9
Subject(s) - nerve guidance conduit , epineurial repair , regeneration (biology) , olfactory ensheathing glia , sciatic nerve , gastrocnemius muscle , medicine , peripheral nerve injury , compound muscle action potential , nerve conduction velocity , anatomy , sciatic nerve injury , nerve injury , surgery , electrophysiology , skeletal muscle , central nervous system , biology , olfactory bulb , microbiology and biotechnology
Autologous nerve grafts are the gold standard treatment for peripheral nerve injury treatment. However, this procedure cannot avoid sacrificing other nerves as a major limitation. The aim of the present study was to evaluate the potential of olfactory ensheathing cells (OECs) embedded in a nerve conduit.