Open AccessHuman Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model
Author(s) -
Chenshen Lam,
Hiba Amer Alsaeedi,
Avin Ee-Hwan Koh,
Mohd Hairul Nizam Harun,
Angela Ng Min Hwei,
Pooi Ling Mok,
Chi D Luu,
Then Kong Yong,
Suresh Kumar Subbiah,
Mae-Lynn Catherine Bastion
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00312-1
Subject(s) - retinal , medicine , dental pulp stem cells , ophthalmology , electroretinography , retinal degeneration , photopic vision , saline , stem cell , erg , retina , macular degeneration , balanced salt solution , anatomy , pathology , chemistry , biology , neuroscience , mesenchymal stem cell , genetics , organic chemistry
Different methods have been used to inject stem cells into the eye for research. We previously explored the intravitreal route. Here, we investigate the efficacy of intravenous and subretinal-transplanted human dental pulp stem cells (DPSCs) in rescuing the photoreceptors of a sodium iodate-induced retinal degeneration model.