Open AccessThe Therapeutic Potential of Amniotic Fluid-Derived Stem Cells on Busulfan-Induced Azoospermia in Adult Rats
Author(s) -
Heba F. Ibrahim,
Safinaz H. Safwat,
Teshreen M. Zeitoun,
Khaled F. El Mulla,
Amira Y. Medwar
Publication year - 2021
Publication title -
tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00309-w
Subject(s) - azoospermia , stem cell , busulfan , andrology , male infertility , pathology , medicine , biology , infertility , microbiology and biotechnology , hematopoietic stem cell transplantation , pregnancy , genetics
Busulfan is an alkylating chemotherapeutic agent that is routinely prescribed for leukemic patients to induce myelo-ablation. However, it also results in azoospermia and infertility in cancer survivors. This research was constructed to explore the possible therapeutic role of amniotic fluid-derived stem cells (AFSCs) in improving busulfan-induced azoospermia in adult rats.
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