Open AccessHyaluronic Acid/Alginate Hydrogel Containing Hepatocyte Growth Factor and Promotion of Vocal Fold Wound Healing
Author(s) -
Jeong Seok Choi,
Se Heang Oh,
Young Mo Kim,
Jae Yol Lim
Publication year - 2020
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00280-6
Subject(s) - hepatocyte growth factor , hyaluronic acid , wound healing , self healing hydrogels , fibronectin , chemistry , immunohistochemistry , fibrosis , hydroxyproline , pathology , extracellular matrix , medicine , immunology , anatomy , biochemistry , receptor , organic chemistry
Hepatocyte growth factor (HGF) has been shown to facilitate vocal fold (VF) wound healing. This study was undertaken to determine whether the therapeutic efficacy of HGF could be enhanced by applying it in hyaluronic acid and alginate (HA/ALG) composite hydrogels into VFs after injury in a rabbit model.