Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver
Author(s) -
Y. H. Kao,
YuChun Lin,
Po–Huang Lee,
Chia-Wei Lin,
PoHan Chen,
Tzong-Shyuan Tai,
YoChen Chang,
Ming-Huei Chou,
Chih-Yang Chang,
CheukKwan Sun
Publication year - 2020
Publication title -
tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00274-4
Subject(s) - mesenchymal stem cell , rhoa , fibronectin , wharton's jelly , cancer research , microbiology and biotechnology , chemistry , stem cell , immunology , extracellular matrix , biology , signal transduction
This study investigated whether xenotransplantation of human Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) reduces thioacetamide (TAA)-induced mouse liver fibrosis and the underlying molecular mechanism.
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