Open AccessInfusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver
Author(s) -
YingHsien Kao,
YuChun Lin,
PoHuang Lee,
Ching-Yi Lin,
PoHan Chen,
Tzong-Shyuan Tai,
Yo-Chen Chang,
Ming-Huei Chou,
ChaoChun Chang,
CheukKwan Sun
Publication year - 2020
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00274-4
Subject(s) - mesenchymal stem cell , rhoa , fibronectin , wharton's jelly , microbiology and biotechnology , chemistry , cancer research , stem cell , immunology , extracellular matrix , biology , signal transduction
This study investigated whether xenotransplantation of human Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) reduces thioacetamide (TAA)-induced mouse liver fibrosis and the underlying molecular mechanism.