Open AccessHuman Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cell
Author(s) -
Mohammad Ali Nilforoushzadeh,
Nasser Aghdami,
Ehsan Taghiabadi
Publication year - 2020
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00266-4
Subject(s) - microvesicles , versican , hair follicle , flow cytometry , dermal papillae , exosome , microbiology and biotechnology , chemistry , western blot , biology , extracellular matrix , biochemistry , proteoglycan , microrna , gene
Hair loss is a prevalent medical problem in both men and women. Maintaining the potential hair inductivity of dermal papilla cells (DPCs) during cell culture is the main factor in hair follicle morphogenesis and regeneration. The present study was conducted to compare the effects of different concentrations of human hair outer root sheath cell (HHORSC) and platelet lysis (PL) exosomes to maintain hair inductivity of the human dermal papilla cells (hDPCs).