Pre-Seeding of Simple Electrospun Scaffolds with a Combination of Endothelial Cells and Fibroblasts Strongly Promotes Angiogenesis | Zendy

Serkan Dıkıcı | Zendy; Frederik Claeyssens | Zendy; Sheila MacNeil | Zendy

Open Access

Pre-Seeding of Simple Electrospun Scaffolds with a Combination of Endothelial Cells and Fibroblasts Strongly Promotes Angiogenesis

Author(s) -

Serkan Dıkıcı,

Frederik Claeyssens,

Sheila MacNeil

Publication year - 2020

Publication title -

tissue engineering and regenerative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.719

H-Index - 23

eISSN - 2212-5469

pISSN - 1738-2696

DOI - 10.1007/s13770-020-00263-7

Subject(s) - in ovo , angiogenesis , chemistry , cell culture , biomedical engineering , microbiology and biotechnology , biology , cancer research , engineering , embryo , genetics

of pro-angiogenic cells into tissue-engineered (TE) constructs (prevascularisation) is a promising approach to overcome delayed neovascularisation of such constructs post-implantation. Accordingly, in this study, we examined the contribution of human dermal microvascular endothelial cells (HDMECs) and human dermal fibroblasts (HDFs) alone and in combination on the formation of new blood vessels in ex-ovo chick chorioallantoic membrane (CAM) assay.

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